BDBM205126 2-{[(3r,6r)-1-{[5-fluoro-2- (1,3-thiazol-2-yl)pyridin-3- yl]carbonyl}-6- methylpiperidin-3-yl]oxy}-3- methylpyridine-4-carbonitrile::US9546152, example 35
SMILES C[C@@H]1CC[C@H](CN1C(=O)c1cc(F)cnc1-c1nccs1)Oc1nccc(C#N)c1C
InChI Key InChIKey=VEEQAPLZSRNWFQ-CXAGYDPISA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 205126
Affinity DataKi: 160nMAssay Description:Radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430) in which the inhibition constant (Ki) is determ...More data for this Ligand-Target Pair
Affinity DataIC50: 453nMAssay Description:The utility of the compounds in accordance with the present invention as orexin receptor OX1R and/or OX2R antagonists may be readily determined witho...More data for this Ligand-Target Pair